Pandora’s prompt: AI and the biological threat

  • Thu, June 4, 2026 • 10:00 am ET
  • Atlantic Council Headquarters
  • 1400 L Street NW • Floor 11
  • Washington, DC 20005

This meeting of the Bipartisan Commission on Biodefense at the Atlantic Council explores the biological threat through the lens of artificial intelligence capabilities.

On Thursday, June 4, at 10:00 a.m. ET, the Bipartisan Commission on Biodefense at the Atlantic Council will host its latest meeting, will discuss the implications of artificial intelligence (AI) advancement for national biodefense.

AI models have progressed at a rapid pace in recent years, offering increasing sophistication and reducing productivity and knowledge barriers. At the same time, our enemies can leverage these tools to assist in the creation of biological weapons. This meeting of the commission will examine how advanced artificial intelligence (AI) models and biological design tools may accelerate biological weapons development, as well as the ways in which AI is changing the biological threat landscape for nation states, terrorist groups, violent extremists, and lone actors. The discussion will also touch upon defensive activities to mitigate the use of AI in biological weapons development that go beyond screening DNA synthesis orders, as well as methods to detect, deny, and disrupt AI-enabled biological weapons activity before use.

This event will not be livestreamed. A recording of the event will be made available at a later date.

New policy: In-person attendees will be required to show photo ID upon arrival, and no on-site registration will be permitted. Guests will not be admitted later than twenty minutes after the event’s start time.

We highly encourage pre-registration by 5:00 p.m. ET on Wednesday, June 3.

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Speakers

Donna Shalala
Co-Chair, Bipartisan Commission on Biodefense,
Atlantic Council

Tom Ridge
Co-Chair, Bipartisan Commission on Biodefense,
Atlantic Council

More speakers to be announced.

Agenda

10:00–10:10 a.m. | Welcome remarks

Speakers

Donna Shalala
Co-Chair,
Bipartisan Commission on Biodefense,
Atlantic Council

Tom Ridge
Co-Chair,
Bipartisan Commission on Biodefense,

Atlantic Council

10:10–11:15 a.m. | Panel one: Prompt to pathogen

Leading AI developers and model evaluators will discuss where current and emerging systems may assist the path from malicious intent to biological weapons development, what safety evaluations have revealed, how guardrails are implemented, when government involvement is involved, and how information hazards are managed.

Speakers to be announced.

11:15 a.m.–12:20 p.m. | Panel two: The threat actors’ new playbook

National security and academic experts will examine how AI changes our adversaries’ calculus of biological weapons development and deployment ranging from nation states to lone wolves.

Speakers to be announced.

12:20–1:05 p.m. | Lunch

Join us for our lunch break.

1:05–2:10 p.m. | Panel three: Beyond the screen

Experts will discuss the layers of defense needed beyond screening DNA synthesis including controlling access to powerful AI tools, strengthening laboratory and supply-chain protections, and building early-warning systems.

Speakers to be announced.

2:10–2:20 p.m. | Break

Break in programming.

2:20–3:25 p.m. | Panel four: The engine room

Technology providers and independent evaluators will discuss the infrastructure beneath AI models themselves such as local computing hardware, cloud capabilities, and automated research tools, and whether government and outside evaluators have adequate visibility into the biological risks these systems may pose.

Speakers to be announced.

3:25–3:35 p.m. | Closing remarks

Featuring

Donna Shalala
Co-Chair,
Bipartisan Commission on Biodefense,
Atlantic Council

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The Bipartisan Commission on Biodefense at the Atlantic Council provides a comprehensive assessment of the state of US biodefense and recommends changes to policy and law that strengthen national biodefense while optimizing biodefense resources.

The Scowcroft Center for Strategy and Security works to develop sustainable, nonpartisan strategies to address the most important security challenges facing the United States and the world.

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