Trade between Latin America and China has multiplied eighteen times since 2000. Between 2005 and 2016, China invested close to $90 billion in the region. In the context of high stakes global trade confrontations, there is a strong motivation for Latin America and China to explore fresh options to upgrade, diversify, and deepen their trade-and-investment relationship, not only to manage peril, but also to leverage new opportunities and strengthen economic cooperation. Deliberate initiatives and strategic actions are required to put in place the policy levers that will help unlock these areas of business opportunity.